Single-stranded specific DNA binding protein, helix destabilizing protein. Reduces formation of secondary DNA structures. Prevents degradation of ssDNA by nucleases. Prevents inhibition of PCR by template DNA contaminants. Improves the efficiency of DNA amplification by Taq Polymerase. Replaces Hot Start method during assembling PCR reaction. Stabilizes single-stranded regions of DNA for site-specific mutagenesis. Aids completion of restriction enzyme digestion. Improves the efficiency of DNA synthesis by T4 DNA Polymerase. Enhances the fidelity of modified T4 Polymerase.